The Center recently published a paper in Sensors and Actuators B: Chemical titled, “Accurate, predictable, repeatable micro-assembly technology for polymer, microfluidic modules.”
The paper details a method for the design, construction, and assembly of modular, polymer-based, microfluidic devices using simple micro-assembly technology, demonstrated to build an integrated fluidic system consisting of vertically stacked modules for carrying out multi-step molecular assays. The biochemical performance of the assembly was comparable to that obtained with benchtop instruments, but took less than 45 min to execute, half the time. It has the potential to replace benchtop protocols for performing complex biological and chemical reactions with low-cost, disposable systems without the need for an expert operator due to the process automation afforded with integrated microfluidic systems.
Read the paper online here: http://www.sciencedirect.com/science/article/pii/S092540051731403X